14 May

New paper – Finding Sequences for over 270 Orphan Enzymes

We’re pleased to announce the publication of our new paper Finding Sequences for over 270 Orphan Enzymes in PLoS ONE.

In this paper, we describe how we used a combined literature, patent, and database evaluation method to find sequences for 275 orphan enzymes. During this research, we learned quite a bit about how orphan enzymes happen. We think we’ve developed some pretty good ways of preventing future orphan enzymes, too.

Once you’ve had a chance to look at the paper, click here to learn more about how to resolve orphan enzymes and deposit enzyme sequences in our Tutorials section.

We also encourage anyone who is interested in how enzyme and sequence data is handled to take a quick survey about sequence deposition and EC numbers.

You can access the database referred to in the paper here.

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The Orphan Enzymes Project is led by Clover Collective
Supported by NIH grant GM086755